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Use With Statin Therapy

See how…niacin complements statin therapy for heart health

Niacin has been shown in studies to work with a type of cholesterol-lowering agent called statins to help support heart health.

SLO-NIACIN® Tablets plus LIPITOR® support heart health

SLIM study* Increased good cholesterol (HDL) Decreased bad cholesterol (LDL) Decreased triglycerides
LIPITOR® (ALONE) ↑ 6%† ↓ 36%† ↓ 26%
SLO-NIACIN® TABLETS (ALONE) ↑ 8% ↓ 12%† ↓ 15%†
SLO-NIACIN® TABLETS + LIPITOR® ↑ 10%† ↓ 43%† ↓ 33%†

Niacin plus ZOCOR® support heart health

  • With proper monitoring and dosing by a healthcare professional, niacin (SLO-NIACIN® Tablets or immediate-release niacin) taken along with ZOCOR® (simvastatin) were shown to have a positive effect on HDL as well as heart health
HATS trial‡ Increased good cholesterol (HDL) Decreased bad cholesterol (LDL) Decreased triglycerides Decreased total cholesterol
NIACIN + ZOCOR® ↑ 26%† ↓ 42%† ↓ 36%† ↓ 31%†

  • Niacin (SLO-NIACIN® Tablets or immediate-release niacin) taken along with ZOCOR® reduced the risk of a cardiovascular event, such as a heart attack, by 90% compared to placebo
  • Niacin (SLO-NIACIN® Tablets or immediate-release niacin) taken along with ZOCOR® helped stop progression of stenosis (arteries closing)

Please remember that people already taking cholesterol-lowering drugs should contact a healthcare professional before taking niacin because of possible side effects and interactions.

Talk to your healthcare professional to find out if SLO-NIACIN® Tablets can help you.

Next: For information on how to take SLO-NIACIN® Tablets


*A 6-month randomized, open-label trial of 42 patients with LDL >130 mg/dL and HDL <45 mg/dL for men (<55 mg/dL for women) who received 3 months of atorvastatin 10 mg/day or incremental doses of SLO-NIACIN® Tablets to 1500 mg/day followed by 3 months of combined treatment.

†Statistically significant P value compared to baseline.

‡A 3-year, double-blind, randomized trial of 160 patients with coronary disease, low HDL, and normal LDL, were assigned to one of four regimens: simvastatin (13 mg +/- 6 mg) plus niacin (2400 mg +/- 2000 mg), antioxidants, simvastatin-niacin plus antioxidants, or placebo.

LIPITOR is a registered trademark of Pfizer, Inc.
ZOCOR is a registered trademark of Merck & Co, Inc.


SLO-NIACIN® Tablets are a niacin dietary supplement shown in clinical studies to raise good cholesterol. With controlled-release niacin, SLO-NIACIN® Tablets gradually release nicotinic acid and are designed to reduce the incidence of flushing and itching commonly associated with niacin use.

Please consult your healthcare professional before taking any dietary supplement.
These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.

Do not use SLO-NIACIN® Tablets if you have a known sensitivity or allergy to niacin. Do not take niacin unless under your doctor's supervision if you have heart disease (particularly, recurrent chest pain or recent heart attack), gallbladder disease, gout, arterial bleeding, glaucoma, diabetes, impaired liver function, stomach ulcers, or are pregnant or lactating. Before taking more than 500 mg/day, call your doctor. If you are taking high blood pressure or cholesterol-lowering drugs, call your doctor before taking niacin due to possible interactions. Case reports of unexplained muscle-related complaints, including discomfort, weakness, or tenderness, have been documented with HMG-CoA Reductase Inhibitors in combination with niacin. Increased uric acid, glucose, and abnormal liver function tests have been reported in persons taking 500 mg/day or more. Discontinue use and call your doctor immediately if you experience persistent flu-like symptoms (nausea, vomiting, not feeling well), loss of appetite, decreased and dark-colored urine, muscle discomfort or weakness, irregular heartbeat or vision problems. Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when beginning, increasing dosage, or changing brands. This safety information is not all-inclusive. For more information, contact your healthcare provider, or call 1-800-654-2299.