Glossary

Cholesterol

Cholesterol is a waxy, fat-like substance found throughout your body that is a key component of cell membranes. It is mainly made by the liver and other tissues, but cholesterol can be absorbed from dietary sources.3

“Flush-free” niacin

“Flush-free” types of niacin formulas that contain ingredients such as inositol hexaniacinate, inositol hexanicotinate, or nicotinamide may not cause flushing, but these types of niacin are not clinically proven to support good cholesterol (HDL).8

Flushing

Flushing is a term used to describe a typically harmless sensation of temporary itching and tingling, feelings of warmth and headache that commonly occur when taking niacin, especially immediate-release niacin.7

High-density lipoprotein (HDL) cholesterol

These particles are thought to carry cholesterol back to the liver for removal from the body. HDL is considered good cholesterol. With HDL, higher numbers are better. A normal level of HDL is higher than 40 mg/dL.4

Lipoprotein

Lipoprotein particles are made up of cholesterol and protein and help move cholesterol through the bloodstream.3

Low-density lipoprotein (LDL) cholesterol

LDL is the major type of lipoprotein that carries cholesterol in the bloodstream throughout the body. LDL is considered bad cholesterol. An optimal level of LDL cholesterol is less than 100 mg/dL.4

Niacin, or nicotinic acid

Niacin, or nicotinic acid, is a type of B vitamin that aids in the function of the digestive system, skin, and nervous system. Niacin, or nicotinic acid, can also help support good cholesterol (HDL) levels.2,5

Total cholesterol

Total cholesterol is an approximate measure of all the cholesterol and triglycerides in your blood. An ideal level of total cholesterol is less than 200 mg/dL.3

Triglycerides

Triglycerides are the chemical form in which most fat exists in food as well as in the body. A normal level of triglycerides is less than 150 mg/dL.3

Vasodilation

Vasodilation is the temporary widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls.9

SLO-NIACIN® Tablets can help maintain good cholesterol (HDL) within the normal range.*2 With a distinctive polygel® controlled-release system, SLO-NIACIN® Tablets gradually deliver nicotinic acid into the body and are designed to help reduce the incidence of flushing that is sometimes associated with niacin use.

IMPORTANT SAFETY INFORMATION

Do not use SLO-NIACIN® Tablets if you have a known sensitivity or allergy to niacin. Do not take niacin unless under your doctor's supervision if you have heart disease (particularly, recurrent chest pain or recent heart attack), gallbladder disease, gout, arterial bleeding, glaucoma, diabetes, impaired liver function, stomach ulcers, or are pregnant or lactating. Before taking 500 mg/day or more, call your doctor. If you are taking high blood pressure or cholesterol-lowering drugs, call your doctor before taking niacin due to possible interactions. Case reports of unexplained muscle-related complaints, including discomfort, weakness, or tenderness, have been documented with HMG-CoA Reductase Inhibitors in combination with niacin. Increased uric acid, glucose, and abnormal liver function tests have been reported in persons taking 500 mg/day or more. Discontinue use and call your doctor immediately if you experience persistent flu-like symptoms (nausea, vomiting, not feeling well), loss of appetite, decreased and dark-colored urine, muscle discomfort or weakness, irregular heartbeat or vision problems. Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when beginning, increasing dosage, or changing brands. This safety information is not all-inclusive. For more information, contact your healthcare provider, or call 1-800-654-2299.

Please consult your healthcare professional before taking any dietary supplement, and especially before taking 500 mg or more of SLO-NIACIN® daily.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.